The Black Death killed between a third and a half of the population of Europe in the 14th century. This website provides a host of information on the Black Death including the low-down on the oriental flea that transmitted the deadly disease.
The Eyewitness to History site has a nice summary of the disease, as has this general site on the Middle Ages, while the BBC site has got plenty of in-depth information including a nice section on the impact.
The History Learning web has got good links with other aspects of Medieval life and a handy section on treatments used at the time. You can also find some really good background on Medieval medicine on the same site.
For an entertaining take on Plague cures have a look at the Terry Deary (of Horrible History fame) video below:
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